Indian Chemical Society

Menu Navigation

Please Log In With Your Credentails ...


All Issues

Synthesis of enantiopure, densely functionalized carbocycles from vinyl nitro-modified carbohydrates

Authors : Chinmoy Manna and Tanmaya Pathak*


DOWNLOAD (164)

Abstract

A powerful, flexible, and stereoselective general strategy for the construction of chirally pure six-membered carbocycles from easily available vinyl nitro-modified hexofuranosides is described. By using a Michael addition reaction followed by ring opening and ring closure, densely functionalized carbasugars decorated with multiple chiral centers are obtained in good overall yields.

Keyword

Nitrovinyl carbohydrates, 1,3-dicarbonyl compounds, Michael addition, enantioselectivity, carbocycles